Collège Doctoral - Doktorandenkollegien

Statistical Physics of Complex Systems

Coventry - Leipzig - Lviv - Nancy

Home
People
Publications
Seminars
Schools
Contacts
PhD positions
Links

Publication

Title Differences in Solution Behavior among Four Semiconductor-Binding Peptides
Authors S. Mitternacht, S. Schnabel, M. Bachmann, W. Janke, and A. Irbäck
Reference J. Phys. Chem. B 111 (2007) 4355-4360
DOI10.1021/jp067581k
Abstract Recent experiments have identified peptides that adhere to GaAs and Si surfaces. Here, we use all-atom Monte Carlo simulations with implicit solvent to investigate the behavior in aqueous solution of four such peptides, all with 12 residues. At room temperature, we find that all four peptides are largely unstructured, which is consistent with experimental data. At the same time, we find that one of the peptides is structurally different and more flexible, as compared to the others. This finding points at structural differences as a possible explanation for differences in adhesion properties among these peptides. By also analyzing designed mutants of two of the peptides, an experimental test of this hypothesis is proposed.


Head of page